Project Z02

Mass spectrometry based proteomics

The Z02 project will provide a broad portfolio of mass spectrometric techniques to the members of the SFB1190. Besides global proteome and PTM analysis, specific focus will be laid on quantitative methods to elucidate the localization, organization and function of protein/protein complexes at different compartmental gates under investigation. These include affinity purification mass spectrometry (AP-MS), proximity labelling mass spectrometry (i.e. APEX and BioID), complexome profiling (e.g. Blue Native mass spectrometry, BN-MS) and protein/protein cross-linking. The Z02 project’s portfolio includes mass spectrometric sample preparation, analysis, data processing and functional annotation.

Principal investigator

Prof. Dr. Henning Urlaub

University Medical Center Göttingen

Department of Clinical Chemistry

Robert-Koch-Straße 40

D-37073 Göttingen

+49 551 39 8506 (phone)

hurlaub(at)gwdg.de (e-mail)

 

Bioanalytical Massspectrometry

Max Planck Institute for Biophysical Chemistry

Am Faßberg 11

D-37077 Göttingen

+49 551 201 1060 (phone)